The Role of the Complement System in Renal Cell Carcinoma

Investigators

Christopher Blosser, MD

Shreeram Akilesh, MD, PhD

WHAT IS THE STUDY?

The purpose of this study is to investigate the role of complement proteins in renal cell carcinoma (RCC), the most common form of kidney cancer. Complement proteins are involved in many processes in our bodies, including immune responses to cancer. Complement proteins are known to be involved in other cancers, but we do not know the role of these proteins in RCC tumors. By better understanding of the role of complements in RCC, we hope to improve treatment options and outcomes for people with RCC in the future. 

WHAT ARE THE GOALS OF THE STUDY?

• Better understanding of the role of complement in RCC
• Study if complements are a prognostic biomarker
• Investigate if complement proteins are targets for the treatment of RCC

WHO CAN JOIN THE STUDY?

• Age: over 18
• Able to speak English
• Undergoing a total nephrectomy at UWMC
• Exclusion: autoimmune disease, coexisting second cancer, liver disease

WHAT DO I DO ONCE I’VE ENROLLED?

• Complete an intake survey
• Provide a blood sample before and during your operation
• Provide a blood sample at 14 and 90-days after your operation
• Let the research team follow your health through your medical records

WHO DO I CONTACT FOR MORE INFORMATION?

Clinical Research Coordinator

Felicia Che

P: 206-685-9648
E: fche@uw.edu
E: cict@uw.edu