HOPE: The Hemodialysis Opioid Prescription Effort Consortium Clinical Center

Patients undergoing long-term dialysis with chronic pain needing opioids will be enrolled in a clinical trial to test multiple strategies to see if they help patients get off prescription opioids. Some patients will receive pain coping skill therapy (PCST) or usual care. After an initial period of treatment, people who are using significant doses of opioids will be randomly assigned to be offered treatment with buprenorphine or usual care, to determine if it allows for a decrease in use of full-agnoist opioids.