This is unpublished

Joseph V.
Bonventre
M.D.
Ph.D.

Joseph V. Bonventre
Scientific Advisory Committee
Pinned
Academic
Samuel A. Levine Professor of Medicine
Professional
Chief of the Renal Unit and Chief of the Division of Biomedical Engineering, Brigham and Women's Hospital, Harvard Medical School
Director of Health Sciences and Technology at Massachusetts General Hospital,
Professor at the Harvard-MIT Health Sciences and Technology, Brigham And Women's Hospital.
Sites of Practice
Harvard University
Brigham And Women's Hospital

Contact

Brigham and Women's Hospital
Harvard Institutes of Medicine Rm. 570A
4 Blackfan Circle
Boston, MA 02115

E: joseph_bonventre@hms.harvard.edu

Education and Training

B.S. with distinction 1970 (Engineering Physics)
Cornell University
Ithaca, NY

M.D. 1976
Harvard Medical School
Harvard-MIT Division of Health Sciences and Technology
Boston and Cambridge, MA

Ph.D. 1979 (Biophysics)
Harvard University
Cambridge, MA

Research Interests

Dr. Bonventre’s research focuses primarily on the study of kidney injury and repair and signal transduction, with a special emphasis on the role of inflammation, biomarkers and stem cells.

SELECTED PUBLICATIONS

Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med. 16(5):535-43, 2010. PMID: 20436483, PMC journal, in process

Vaidya VS, Ozer JS, Dieterle F, Collings FB, Ramirez V, Troth S, Muniappa N, Thudium D, Gerhold D, Holder DJ, Bobadilla NA, Marrer E, Perentes E, Cordier A, Vonderscher J, Maurer G, Goering PL, Sistare FD, Bonventre JV. Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies. Nat Biotechnol. 28(5):478-85, 2010. PMCID:PMC2885849

Bonventre JV, Vaidya VS, Schmouder R, Feig P, Dieterle F. Next-generation biomarkers for detecting kidney toxicity. Nat Biotechnol. 28(5):436-40, 2010. PMCID: PMC3033582

Humphreys BD, Czerniak S, DiRocco DP, Hasnain W, Cheema R, Bonventre JV. Repair of injured proximal tubule does not involve specialized progenitors. Proc Natl Acad Sci U S A. 108(22):9226-31, 2011. PMCID: PMC3107336

Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Imperfect Gold Standards for Kidney Injury Biomarker Evaluation. J Am Soc Nephrol. 23(1):13-21, 2012. PMID: 22021710

Bonventre JV, Yang L. Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest. 121(11):4210-21, 2011. PMCID: PMC3204829