PEOPLE > Bonnie W. Ramsey, M.D.

Bonnie W. Ramsey, M.D.

Director, Center for Clinical and Translational Research at Seattle Children’s Research Institute; Professor, Pediatrics, University of Washington

Education and Training

Research Interests

Bonnie Ramsey, board certified in Pediatric Pulmonary Medicine, has spent her career focused on clinical care and research in the field of Cystic Fibrosis (CF). She has a 16 year history of leadership in clinical and translational research at the University of Washington and Seattle Children's Hospital.

She established and directed the NCRR supported Pediatric Clinical Research Center (PCRC) from 1996-2007, a satellite unit of the UWCRC. In 1998, with support of the CF Foundation, she developed the Cystic Fibrosis Therapeutics Development Network Coordinating Center which has provided clinical, statistical, data management, and/or regulatory support for over 90 multi-center therapeutic trials in the past 13 years. Since 2007, she has served as the co-director of the Institute of Translational Research with oversight of the Child Health research programs. She has been very involved in the national CTSA Consortium having served as the Chair of the Child Health Oversight Committee (CC-CHOC) from 2009-2010. During that time period, she led the initiative to successfully form an affiliation between the CC-CHOC and the American Pediatric Societies.

Since 2008, Ramsey has directed the Center for Clinical and Translational Research (CCTR) at Seattle Children's Research Institute which provides support services for child health researchers in close collaboration with ITHS. Through her leadership roles in both the ITHS and CCTR, she enjoys mentoring junior faculty as they develop careers in translational research. She has a long history of supporting and training fellows and junior faculty in Pediatric Pulmonary Medicine as well as basic scientists in the field of Cystic Fibrosis.

SELECTED PUBLICATIONS

View Publications on PubMed

Ramsey BW, Davies J, McElvaney NG, Tullis E, Bell SC, Dfevinek P, Griese M, McKone E, Wainwright C, Konstan M, Moss R, Ratjen F, Sermet-Gaudelus I, Rowe SM, Qunming D, Rodriguez S, Yen K, Ordonez C, Elborn JS on behalf of the VXO8-770-102 Study Group. A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. New Engl J Med 2011; 365 (18):1663-1672.

Rowe SM, Borowitz DS, Burns JL, Clancy JP, Donaldson SH, Retsch-Bogart G, Sagel SD, Ramsey BW. Progress in cystic fibrosis and the CF Therapeutics Development Network. Thorax 2012;67(10):882-90.

Hoffman LR, Pope CE, Hayden HS, Heltshe S, Levy R, McNamara S, Jacobs MA, Rohmer L, Radey M, Ramsey BW, Brittnacher MJ, Borenstein E, Miller SI. Escherichia coli dysbiosis correlates with gastrointestinal dysfunction in children with cystic fibrosis. Clin Infect Dis 2014 58(3):396-9. PMID: 24178246

Quon B, Goss C, Ramsey BW. Inhaled antibiotics for lower airway infections. Annals of the American Thoracic Society 2014;11:425-434.

Rowe SM, Heltshe SL, Gonska T, Donaldson SH, Borowitz D, Gelfond D, Sagel SD, Khan U, Mayer-Hamblett N, Van Dalfsen JM, Joseloft E, Ramsey BW. Clinical mechanism of the CFTR potentiator ivacaftor in G551D-mediated cystic fibrosis. Am J Respir Crit Care Med 2014 (epub ahead of print).

Retsch-Bogart GZ, Van Dalfsen JM, Marshall BC, George C, Pilewski JM, Nelson EC, Goss, CH, Ramsey BW. Highly Effective Cystic Fibrosis Clinical Research Teams: Critical Success Factors. J Gen Intern Med DOI 10.1007/s11606-014-2896-8 2014.