This is unpublished

Joseph V.
Bonventre
MD
PhD

Joseph V. Bonventre
Scientific Advisory Committee
Pinned
Academic
Samuel A. Levine Professor of Medicine
Professional
Samuel A Levine Distinguished Professor of Medicine, Harvard Medical School
Constantine L Hampers Distinguished Professor of Medicine
Chief Emeritus of the Renal Division
Founding Chief of the Division of Engineering in Medicine
Brigham and Women’s Hospital
Sites of Practice
Harvard University
Brigham And Women's Hospital

Contact

Brigham and Women's Hospital
Harvard Institutes of Medicine Rm. 570A
4 Blackfan Circle
Boston, MA 02115

E: joseph_bonventre@hms.harvard.edu

Education and Training

B.S. with distinction 1970 (Engineering Physics)
Cornell University
Ithaca, NY

M.D. 1976
Harvard Medical School
Harvard-MIT Division of Health Sciences and Technology
Boston and Cambridge, MA

Ph.D. 1979 (Biophysics)
Harvard University
Cambridge, MA

Research Interests

Dr. Bonventre’s research focuses primarily on the study of kidney injury and repair and signal transduction, with a special emphasis on the role of inflammation, biomarkers and stem cells.

SELECTED PUBLICATIONS

Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med. 16(5):535-43, 2010. PMID: 20436483, PMC journal, in process

Vaidya VS, Ozer JS, Dieterle F, Collings FB, Ramirez V, Troth S, Muniappa N, Thudium D, Gerhold D, Holder DJ, Bobadilla NA, Marrer E, Perentes E, Cordier A, Vonderscher J, Maurer G, Goering PL, Sistare FD, Bonventre JV. Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies. Nat Biotechnol. 28(5):478-85, 2010. PMCID:PMC2885849

Bonventre JV, Vaidya VS, Schmouder R, Feig P, Dieterle F. Next-generation biomarkers for detecting kidney toxicity. Nat Biotechnol. 28(5):436-40, 2010. PMCID: PMC3033582

Humphreys BD, Czerniak S, DiRocco DP, Hasnain W, Cheema R, Bonventre JV. Repair of injured proximal tubule does not involve specialized progenitors. Proc Natl Acad Sci U S A. 108(22):9226-31, 2011. PMCID: PMC3107336

Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Imperfect Gold Standards for Kidney Injury Biomarker Evaluation. J Am Soc Nephrol. 23(1):13-21, 2012. PMID: 22021710

Bonventre JV, Yang L. Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest. 121(11):4210-21, 2011. PMCID: PMC3204829